Minocycline is a tetracycline antibiotic that is frequently used for treatment of moderate to severe acne vulgaris. Minocycline only needs to be taken once or twice a day and can be taken with food, but it is also more expensive than the other tetracyclines. Concerns have also been expressed over its safety and a few deaths have been reported. Even among skin doctors, the use of minocycline is questionable. So far there is not a single decent study that has shown that minocycline is better than other tetracyclines. Considering that the drug is expensive and has undesirable side effects, I personally would not recommend it.
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